2. Gastrointestinal microbiome:

Intermittent fasting through its restriction of food during the night enhances food digestion and metabolism as gastric emptying and gastrointestinal secretions and blood flow are way greater during the daytime than at night .it also directly influences the gut microbiome which is a complex and variable community of microorganisms that reside the gastrointestinal tract and are responsible for absorption of the toxins from the body and enhancing the overall health of the GIT.
studies have found that microbiota in obese people harvests more energy from the diet than in lean people which makes obese people need more energy absorption and storage another important factor is obesity-related gut changes that increase the permeability of the gut and promotes bacterial translocation one of the hallmarks of obesity-related inflammatory activity and the cause of many obesity-related comorbidities.