Pulmonary Edema | Symptoms, Causes and Treatment

7. Angiotensin II receptor blockers

Patients who cannot tolerate ACE inhibitors can be given Angiotensin II receptor blockers (ARBs), which produce the same outcome without as many side effects.

Throughout the complex mechanism of action of ACE inhibitors, the normal rate of breakdown of a peptide called Bradykinin is decreased. Accumulation of Bradykinin causes a persistent dry cough as long as the medication is being taken in some patients. This is not seen with ARBs. An example of an Angiotensin II receptor blocker is Valsartan.