Unveiling Effective Gastritis Treatments: A Comprehensive Review

2. Chronic gastritis treatment

• Basics of chronic gastritis treatment

There are different causes of chronic gastritis, but the most commonly known is Helicobacter pylori infection. This type of infection can trigger both acute and chronic gastritis symptoms. Another known cause of chronic gastritis is known as lymphocytic gastritis. However, once again, the only entity with an excellent background and treatment protocol is H pylori gastritis.

Other entities of chronic gastritis lack many studies, enough evidence, and well-established protocols to treat the disease. One suitable example is lymphocytic gastritis, which is known to improve with omeprazole, but some patients have experienced spontaneous healing.

Pharmacotherapy for H. pylori in chronic gastritis is similar to that of acute gastritis, as we will see below. However, in such cases, doctors should also consider the possibility of stomach cancer, especially in patients with a long history of symptoms.

• H. pylori treatment in chronic gastritis

There’s no easy cure for Helicobacter pylori infections, and that’s why all treatment protocols include multidrug therapy instead of one or two drugs. As mentioned with acute gastritis, multidrug treatment for H. pylori consists of an antimicrobial agent, which includes antibiotics that attack H pylori such as amoxicillin, clarithromycin, tetracycline, furazolidone, or metronidazole. These drugs should be used in combination because monotherapy almost invariably leads to antibiotic resistance.

The FDA currently approves five treatment regimes for H pylori in chronic gastritis. The traditional approach uses bismuth, metronidazole, and tetracycline. This treatment is sold under the name Helidac. Besides this conventional approach, three other combinations with clarithromycin are equally effective. However, in chronic gastritis, it is even more common that patients need a combination of regimes with bismuth-based therapy followed by clarithromycin-based treatment for complete eradication.