8. Leukemia

One of the most concerning causes of skin rash in children and adults is leukemia. This is a type of blood cancer that causes an overproduction of white blood cells, which are liberated into the blood in an immature state. As the disease progresses, the excess white blood cells may also invade the bone marrow and halt the differentiation of platelets. In this stage of the disease, leukemia patients have different hemorrhagic features, including spontaneous bleeding and hemorrhagic skin rash similar to that described above. The incidence of spots and bruises in the skin and the reduction of platelet count in patients with leukemia are signs of bad prognosis.