2. Slow motion and tiredness
Fatigue is associated with clinical depression and the same happens with bipolar patients in a depressive episode. These patients feel overly tired, and their energy levels are dramatically reduced. They usually become slow and clumsy; a symptom clinically named psychomotor retardation. It results from a defective secretion of the neurotransmitter dopamine in brain centres associated with the motor cortex, such as the thalamus.
Diminished body movements are often associated with diminished thoughts and speed of thought. It is not only associated with bipolar disorders but may also be the result of certain drugs and medical conditions that also trigger slow mental activity and sluggish body movements.