2) Rheumatoid Arthritis (RA)
Rheumatoid Arthritis is an auto-immune disorder in which the human antibodies attack their own tissues by mistake, particularly the synovial membrane lining the joints. RA usually affects small joints first, yet an atypical course of rheumatoid could occur affecting knee joints.
Rheumatoid arthritis could affect joints on one or both sides, it is often presented with pain, stiffness, redness, and joint swelling that gets worse in the early morning. Rheumatologists usually choose a stepwise approach in treating RA as they start with immune-suppressive drugs. Late-stage RA that showed irreversible deformity in the knee joint indicates knee replacement surgery.