3) Hemophilia
Hemophilia is a hereditary coagulation disorder in which the body can’t synthesize a coagulative factor. Patients diagnosed with hemophilia have more tendency to bleed anywhere including joints causing a condition called hemophilic arthropathy.
Hemophilic arthropathy of the knee joint causes inflammatory responses that eventually lead to the destruction of the joint cartilage and synovial membrane. Uncontrolled hemophilic arthropathy of the knee joint may result in a disability and in such a case, a knee replacement surgery is recommended.