4) Gout
Gout is a form of arthritis characterized by an increased level of uric acid in the blood. Uric acid, which is a natural product of the metabolism of proteins and excreted mostly by the kidneys, accumulates in the bloodstream in some susceptible patients. Elevation of the uric acid level in the blood leads to its deposition in the joints causing severe inflammation, pain, stiffness, and eventually destruction.
Although gout usually affects the joint of the big toe first, it could also affect the knee joint at some point of its progression which will indicate knee arthroplasty.
