5. Fatigue
Fatigue is one of the most frequent symptoms seen in medical practice. It is usually accompanied by other symptoms and is a significant component of a wide variety of syndromes or clinical conditions. Fatigue, also known as lassitude, can be considered a normal sensation when it occurs after a day of work or intense physical effort. However, when fatigue can no longer be considered a normal response to the day’s demands and becomes a chronic condition, and cannot be easily attributed to known triggers, it is considered an abnormal state and some underlying pathological reason must be considered.
Fatigue can be caused by infections, metabolic disorders, renal failure, hepatic failure, pulmonary distress, cardiovascular disease, neurovascular disease, and blood disorders. In the case of Hyperglycemia, most experts agree that the feeling of fatigue arises from the development of acidosis at the muscle fiber level. Endocrine alterations, which are known to generate states of hypermetabolism with increased energy consumption, electrolyte loss, exaggerated protein catabolism, and nutrient deficiency can also contribute to the appearance of chronic fatigue.
