E) Stage IV Colon Cancer
Stage 4 is the most advanced stage and indicates metastasis of the tumor tissue. In this stage, the tumor tissue spreads to distant organs such as the liver, lungs or even the brain. Stage 4 is also further divided into two classes: Stage IVA and Stage IVB. When cancer affects only one organ, it is known as Stage IVA of colorectal cancer. If more than one organ is involved, it is known as Stage IVB of colon cancer.