What differentiates pathologic fractures is the force required to produce them. Since the bone tissue is severely affected by multiple myeloma, it becomes weakened and more susceptible to fractures. These fractures are prevalent, and they can be severe or very mild (as in smaller bone lesions). However, they are always revealed in an X-ray in 93% of patients, and they are naturally more common in the lower extremities. Pain is more common when pathologic fractures involve 50% of the diameter of the bone. In smaller fractures, dull pain or bony tenderness is more common.