Leukemia Symptoms; 11 Common Leukemia Signs & Symptoms

4. Chills and night sweat

One of the most common symptoms associated with fever is chills. This is a common response the body has to the increase in temperature threshold by the brain. The command of increasing body temperature comes from the central nervous system, and when it reaches the muscle tissue, it starts burning energy with jerking movements (chills) to transform stored energy into heat.

That is the reason why patients with leukemia often wake up drenched in their own sweat. Night sweats are very uncomfortable and may result in severe sleep problems that contribute to fatigue. When leukemia patients have an infection, they are even more likely to undergo night sweats and fever. It is also a common side effect of chemotherapy.